Stablepharma
Stablepharma Ltd is a UK-based biopharmaceutical company known for developing a range of fridge-free vaccines using its branded technology to eliminate the need for the global cold chain and reduce the global vaccine wastage.[1][2]
Stablepharma was the winner of the 2024 Fierce Life Sciences Innovation Biotech Award[3] and a finalist for the Pharma Industry Awards UK 2024 Biotech of the year.[4]
History
Stablepharma was founded in 2012 after the company’s Chairman and Founder, Dr Bruce Roser identified and patented the process of using Trehalose to achieve a state of suspended animation in a sugar glass to thermally stabilise a range of vaccines.[5][6]
In September 2023, Stablepharma secured a second Innovate UK Grant, in partnership with the Hospital of Southampton NHS Foundation Trust] to commence a bridge-funding round.[7]
On the 18th of December 2024, Stablepharma submitted a Clinical Trial Application (CTA) to the UK regulators, Medicines and Healthcare products Regulatory Agency (MHRA), for a trial with SPVX02, a booster vaccine for the prevention of tetanus and diphtheria infection.[8] The submission of the CTA represents a significant milestone for Stablepharma and secures its positioning as a clinical-stage biotechnology company.[8]
Vaccine technology
Stablepharma offers a technology platform known as StablevaX which has been designed to meet the criteria for usage required by the World Health Organisation (WHO) and its use in the field for immunisation programmes requires limited or no training.[9]
In collaboration with EU manufacturer BB-NCIPD Ltd (Bul Bio), Stablepharma is producing a fridge-free Tetanus diphtheria (SPVX02) vaccine, a pharmaceutical product for the prevention of Tetanus and Diphtheria and also a fridge-free Tetanus (SPVX06) vaccine for the prevention of Tetanus.[10]
Award and honors
References
- ↑ "Fridge-Free COVID-19 Vaccines a Possibility"
- ↑ Kate Robinson& Laura Elizabeth Lansdowne,"Developing Thermostable Vaccines To Improve Accessibility Worldwide"
- ↑ Template:Cite news
- ↑ 4.0 4.1 "Innovation takes centre stage at Pharma Industry Awards UK 2024"
- ↑ Angeli Mehta,"Can chemistry thaw the vaccine cold chain?"
- ↑ "The imperative of fridge-free vaccines"
- ↑ "Stablepharma secures Innovate UK grant, bridge funding round to launch"
- ↑ 8.0 8.1 "Stablepharma achieve significant milestone in the GMP manufacture of a fridge-free Td vaccine"
- ↑ Ronan Leonard,"Stablepharma Ltd and BB-NCIPD Ltd produce the world’s first fridge free Tetanus diphtheria vaccine"
- ↑ Ronan Leonard,"Stablepharma and Partner BB-NCIPD Ltd (Bul Bio) sign a second exclusive supply agreement to develop a fridge-free Tetanus mono vaccine"
- ↑ "2024 Fierce Life Sciences Innovation Awards Winners"